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SIV辅助调控蛋白在小鼠模型中对SIV结构蛋白Gag,Pol和Env免疫原性的影响 张寅峰 299
Bridging Bench to Clinic: Roles of Animal Models for Post‐Genomics Drug Discovery.. Chi‐Wai Wong 24
Integrated Approaches for Discovering Novel Drugs From Microbial Natural Products Lixin Zhang 21
通过分子内C(sp2)−H羰基化反应合成4(3H)-喹唑啉酮类化合物 马彬 21
Ribozyme-catalyzed dipeptide synthesis in monovalent metal ions alone Sun, Lele 20
选择性FGFR不可逆抑制剂及其低氧激活型前药的设计、合成及生物活性研究 李学强 19
棕榈酰肉碱酰基转移酶1c的功能研究 高学飞 18
人脂联素受体1和2的真核表达 张烁 17
Targeting the trafficking of MT-MMP for anti-cancer therapy Duanqing Pei 16
研究领域的主题发展趋势分析方法研究——基于多重共现的视角 庞弘燊 15
Rosa26-targeted swine models for stable gene over-expression and Cre-mediated line.. Li, Xiaoping 15
A mechanism for vocal-respiratory coupling in the mammalian parabrachial nucleus Michael Smotherman 15
The epitope study of a-fodrin autoantibody in primary Sjögren’s syndrome Chen, Q. 14
以疟原虫为载体表达 GPC3 蛋白的肝癌疫苗及其免疫机理的研究 刘权 13
Bats Are Natural Reservoirs of SARS-Like Coronaviruses Wendong Li 12
1、N-苄基酰胺在N-溴代丁二酰亚胺作用下室温脱苄基反应的研究 2、细胞周期依赖性激酶小.. 况利平 12
Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles... Wei Lian 11
New benzimidazole-2-urea derivates as tubulin inhibitors Wang, Wenna 11
Palmitoylation and Membrane Cholesterol Stabilize mu-Opioid Receptor Homodimerizat.. Hui Zheng 11
Hypoxia dysregulates the production of adiponectin and plasminogen activator inhib.. Baoying Chen 11
Characterization of microsatellite loci in fulvous fruit bat Rousettus leschenault.. P. Y. HUA 11
骨科相关中药对雌激素受体的激活作用 王海彬 11
脐带血干细胞体外维持及UM171在人多能干细胞定向造血分化中的作用研究 李学家 11
Rapid isothermal detection assay: a probe amplification method for the detection o.. Gao, Wenjuan 10
Generation of gene-target dogs using CRISPR/Cas9 system Zou, Qingjian 10
Matrix metalloproteinases target protease-activated receptors on the tumor cell su.. DuanqingPei 10
Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases Haitao Yang 10
Sorting Nexin 10 Induces Giant Vacuoles in Mammalian Cells Baoming Qin 10
重组α-胞衬蛋白的表达及其在原发性干燥综合征临床研究中的意义 陈巧林 10
蛋白酶体抑制剂硼替佐米诱导髓系白血病细胞株HL60凋亡的机制研究 扶云碧 10
利用哺乳动物细胞双杂交体系研究仙灵骨葆对雌激素受体的作用 王小娟 10
Attenuation of cGVHD by C5a/C5aR blockade is associated with increased frequency o.. Yulian Wang 10
新型M2抑制剂蒎烷胺衍生物的设计与合成和有机小分子催化的不对称Michael反应研究 陈省委 10
H3K27me3去甲基化酶JMJD3和UTX在体细胞重编程中的作用和机制研究 张辉 10
Direct generation of ES-like cells from unmodified mouse embryonic fibroblasts by .. Qin, Dajiang 9
Design and synthesis of novel soluble 2,5-diketopiperazine derivatives as potentia.. Liao, Shengrong 9
Conversion of non-adipogenic fibroblasts into adipocytes by a defined hormone mixt.. Nie, Tao 9
C-Myb(+) Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tis.. Hoeffel, Guillaume 9
Reprogramming cells with synthetic proteins Yang, Xiaoxiao 9
cDNA microarray analysis of differential gene expression and regulation in clinica.. Zheng Xu 9
HIV蛋白酶抑制剂或其衍生物抗疟疾、抗肿瘤作用及其机理的研究 何正祥 9
基于腺病毒载体的新型HIV/SIV疫苗及免疫策略的开发 孙彩军 9
Cryotherapy protocols for metastatic breast cancer after failure of radical surger.. Niu, Lizhi 9
铜催化三氟甲基化反应研究 雷健 9
异质性线粒体DNA互补规律研究 杨亮 9
敲除恒河猴造血干细胞CCR5基因治疗SIV感染的实验研究 余松林 9
人源SNX13蛋白的结构生物学研究 朱家滨 9
Doping effect of Al2O3 and CeO2 on Fe2O3 support for gold catalyst in CO oxidation.. Liu, Ruihui 8
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction Zhang, Wenqian 8
Arthpyrones A-C, Pyridone Alkaloids from a Sponge-Derived Fungus Arthrinium arundi.. Wang, Junfeng 8
Eight new polyketide metabolites from the fungus Pestalotiopsis vaccinii endogenou.. Wang, Junfeng 8
Cholesterol level influences opioids signaling in cell models and analgesia in mic.. Hui Zheng 8
The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Doma.. Tan, M. H. Eileen 8
白色脂肪细胞棕色化相关药物的筛选及机制研究 毛刘锋 8
基于内吞作用的外源线粒体导入细胞探索 刘雪宾 8
恒河猴共感染模型中SIV与疟原虫的相互影响及恒河猴T细胞受体β链多样性分析 刘广杰 8
先天性高胰岛素血症和1型多发性内分泌腺瘤干细胞模型的建立 郭东升 8
Current approaches to reduce or eliminate mitochondrial DNA mutations Yang, Liang 7
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9m.. Bao, Xichen 7
Design and synthesis of N-(4-aminopyridin-2-yl)amides as B-Raf(V600E) inhibitors Li, Xiaokai 7
A Transition-Metal-Free Synthesis of Arylcarboxyamides from Aryl Diazonium Salts a.. Xia, Zhonghua 7
Effect of beta(3)-Adrenergic Receptor on Atrial L-type Ca2+ Current in Rats with C.. Li, Biao 7
Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivativ.. Liao, Sheng-Rong 7
Asteltoxins with Antiviral Activities from the Marine Sponge-Derived Fungus Asperg.. Tian, Yong-Qi 7
Effects of SOX2 on Proliferation, Migration and Adhesion of Human Dental Pulp Stem.. Liu, Pengfei 7
Transgenic expression of human cytoxic T-lymphocyte associated antigen4-Immunoglob.. Wang, Yong 7
A multiplexer liquidchip technology for detecting single nucleotide polymorphisms .. Zhu, Zeyao 7
Role of pncA and rpsA Gene Sequencing in Detection of Pyrazinamide Resistance in M.. Tan, Yaoju 7
Factors triggering type III secretion in Pseudomonas aeruginosa Jaewha Kim 7
Immune responses in Balb/c mice induced by a candidate SARS-CoV inactivated vaccin.. Chuan-hai Zhang 7
Adiponectin Modulates the Glycogen Synthase Kinase-3β/β-Catenin Signaling Pathwa.. Yu Wang 7
Chinese Herbal Drug Industry: Past, Present and Future Lixin Zhang 7
Preparation of monoclonal antibodies against a derivative of semicarbazide as a me.. Aizhong Gao 7
Beauvericin对药物代谢酶P450s的抑制作用及其在大鼠体内的药代动力学研究 梅黎 7
雌激素相关受体alpha调控骨骼肌细胞代谢的功能研究 陈利华 7
单纯疱疹感染对寄主的影响和华南地区儿童临床分离株阿昔洛韦抗性及进化研究 王弋 7
An efficient method for the synthesis of disubstituted thioureas via the reaction .. Yin, Biaolin 7
葡萄糖激酶、elaiophylin糖基转移酶和富亮氨酸重复激酶2的结构功能研究 刘强 7
MKK6提高体细胞重编程效率机制的研究 赵丹芸 7
运用反向遗传技术制备携带荧光素酶的可活体示踪感染的流感病毒及新型减毒流感病毒的研究 董振远 7
疟原虫感染对接受抗病毒治疗的SIV阳性恒河猴病毒储存库影响的实验研究 詹晓勇 7
JMJD3介导的H3K27me3去甲基化促进体细胞重编程 黄颖华 7
非金属媒介/催化的C-N成键反应用于构建含氮杂环/吲哚双酰胺类化合物的抗流感病毒活性的.. 贺益苗 7
官能化的异腈在含氮杂环合成中的应用 王见 7
基于核酸等温扩增的单核苷酸多态性生物传感器的构建 萧卓 7
基于噬菌体展示技术的抗CD3单链抗体12F6稳定性优化研究 刘强 7
Exploring novel bioactive compounds from marine microbes Lixin Zhang 6
Tbx3 isoforms are involved in pluripotency maintaining through distinct regulation.. Zhao, Danyun 6
Site selective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6.. Liao, Sheng-Rong 6
Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated.. Wei, Shu 6
Synergy between Proteasome Inhibitors and Imatinib Mesylate in Chronic Myeloid Leu.. Hu, Zheng 6
The C-terminal Pentapeptide of Nanog Tryptophan Repeat Domain Interacts with Nac1 .. Ma, Tianhua 6
Amycolatopsis marina sp nov., an actinomycete isolated from an ocean sediment Bian, Jiang 6
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraft.. Ye, Wei 6
Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Dr.. Ai, Yong 6
Isolation and characterization of a T-superfamily conotoxin from Conus litteratus .. Liu, Junliang 6
Adenoviral cardiotrophin-1 transfer improves survival and early graft function aft.. Song, Jun 6
Therapeutic action of bone marrow-derived stem cells against acute kidney injury Liu, Pengfei 6
Ralstonia solanacearum fatty acid composition is determined by interaction of two .. Feng, Sai-Xiang 6
Novel morpholin-3-one fused quinazoline derivatives as EGFR tyrosine kinase inhibi.. Qin, Xuemei 6
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利用相同遗传背景的诱导多能干细胞模型研究帕金森病 赵平 3
帕金森综合症猪模型的建立及异种器官移植供体猪的培育 周小青 3
敲除恒河猴造血干细胞CCR5基因治疗SIV感染的实验研究 余松林 3
Integrated Approaches for Discovering Novel Drugs From Microbial Natural Products Lixin Zhang 2
Current approaches to reduce or eliminate mitochondrial DNA mutations Yang, Liang 2
Doping effect of Al2O3 and CeO2 on Fe2O3 support for gold catalyst in CO oxidation.. Liu, Ruihui 2
Identification of GZD824 as an Orally Bioavailable Inhibitor That Targets Phosphor.. Ren, Xiaomei 2
Neural progenitor cells from human induced pluripotent stem cells generated less a.. Huang Ke 2
Enzyme-amplified electronic logic gates based on split/intact aptamers Chen, Junhua 2
The epitope study of a-fodrin autoantibody in primary Sjögren’s syndrome Chen, Q. 2
Bats Are Natural Reservoirs of SARS-Like Coronaviruses Wendong Li 2
Matrix metalloproteinases target protease-activated receptors on the tumor cell su.. DuanqingPei 2
Characterization of microsatellite loci in fulvous fruit bat Rousettus leschenault.. P. Y. HUA 2
Endoplasmic reticulum stress links hepatitis C virus RNA replication to wild-type .. Yao, W. 2
基于AVIP技术的全抗原治疗性SIV疫苗及新型分子佐剂的研究 肖利军 2
基于等温链置换扩增的缺失型α-地中海贫血检测方法研究 余路新 2
霉酚酸(MPA)抗胃癌的分子及细胞生物学机制研究 顿博影 2
小鼠体细胞重编程过程中染色质的开放 陈可实 2
通过优化Kex2酶切效率提高Pichia pastoris酵母分泌重组蛋白量的研究 杨松 2
运用反向遗传技术制备携带荧光素酶的可活体示踪感染的流感病毒及新型减毒流感病毒的研究 董振远 2
2型登革热病毒蛋白酶NS2B-NS3p活性构象研究及友菌素糖基转移酶结构生物学研究 李华 2
CRISPR/Cas9系统介导家兔多基因打靶的研究及IL2RG基因敲除兔的建立 颜泉梅 2
LincRNA-p21调控小鼠体细胞重编程的机理研究 吴海涛 2
MiR-190和miR-128对成体小鼠海马神经发生以及空间学习记忆的影响 李文 2
VLDL相关宿主因子HNF4α与PLA2GXIIB调节可感染性HCV生成的发现与机制研究 姜含芳 2
白色脂肪细胞棕色化相关药物的筛选及机制研究 毛刘锋 2
单核苷酸多态性检测方法的建立及核酸等温扩增技术在食源性致病菌检测中的应用 吴薇 2
钯催化的C3位取代吲哚的合成方法研究 胡姿卫 2
BAF染色质重构复合物和BET家族蛋白Brd4调控体细胞重编程的机理研究 刘龙奇 2
HDAC家族调控体细胞重编程的机理研究 庄强 2
免疫缺陷猪模型的建立 黄姣 2
通过分子内C(sp2)-H键官能化反应构建含氮杂环的研究 梁冬冬 2
铜催化三氟甲基化反应研究 雷健 2
异质性线粒体DNA互补规律研究 杨亮 2
ANGPTL7调节造血干细胞及祖细胞的机理研究 肖毅仁 2
CRISPR/Cas9介导的基因激活系统诱导胚胎干细胞向胚外细胞谱系转换 魏姝 2
CRISPR/Cas9介导的热带爪蛙基因敲除应用及基因插入技术平台建立 崔燕 2
H3K27me3去甲基化酶JMJD3和UTX在体细胞重编程中的作用和机制研究 张辉 2
Kv1.3离子通道参与调节神经干细胞的神经分化和成熟的研究 周雨叶 2
非金属媒介/催化的C-N成键反应用于构建含氮杂环/吲哚双酰胺类化合物的抗流感病毒活性的.. 贺益苗 2
恒河猴共感染模型中SIV与疟原虫的相互影响及恒河猴T细胞受体β链多样性分析 刘广杰 2
基于核酸等温扩增的单核苷酸多态性生物传感器的构建 萧卓 2
FAH基因敲除肝损伤模型兔的建立及肝细胞移植治疗 李黎 2
RNA结合蛋白DDX5对体细胞重编程的调控作用及其机理研究 李欢欢 2
基于脂代谢的多能性获得与维持机制研究 邬毅 2
先天性高胰岛素血症和1型多发性内分泌腺瘤干细胞模型的建立 郭东升 2
以疟原虫为载体表达 GPC3 蛋白的肝癌疫苗及其免疫机理的研究 刘权 2
Antituberculosis compounds from a deep-sea-derived fungus Aspergillus sp SCSIO Ind.. Luo, Xiaowei 2
Copper-Catalyzed Bromodifluoroacetylation of Alkenes with Ethyl Bromodifluoroaceta.. Li, Dengke 2
Exploring novel bioactive compounds from marine microbes Lixin Zhang 1
Identification of EGFR kinase domain mutations among lung cancer patients in China.. Bao Ming QIN 1
An Enhanced Strip Biosensor for Rapid and Sensitive Detection of Histone Methylati.. Ge, Chenchen 1
Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated.. Wei, Shu 1
Colorimetric Detection of Copper(II) Ion Using Click Chemistry and Hemin/G-Quadrup.. Ge, Chenchen 1
Prevention of Needle-Tract Seeding by Two-Step Freezing after Lung Cancer Biopsy Mu, Feng 1
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraft.. Ye, Wei 1
Expedient Construction of the Ziegler Intermediate Useful for the Synthesis of For.. Ye, Heping 1
Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Dr.. Ai, Yong 1
Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and .. Fu, Wei-Ming 1
Ribozyme-catalyzed dipeptide synthesis in monovalent metal ions alone Sun, Lele 1
Protein kinase C delta null mice exhibit structural alterations in articular surfa.. Yang, Xiaohong 1
Cell death-inducing DFFA-like effector B contributes to assembly of hepatitis C vi.. Cai, H. 1
Ralstonia solanacearum fatty acid composition is determined by interaction of two .. Feng, Sai-Xiang 1
Haze, health and disease Preface Chung, Kian Fan 1
EM23, A Natural Sesquiterpene Lactone from Elephantopus mollis, Induces Apoptosis .. Li, Hongyu 1
Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors.. Bai, Jinhong 1
Platinum-containing compound platinum pyrithione is stronger and safer than cispla.. Zhao, Chong 1
A Transition-Metal-Free Synthesis of Arylcarboxyamides from Aryl Diazonium Salts a.. Xia, Zhonghua 1
Combination treatment with comprehensive cryoablation and immunotherapy in metasta.. Niu, Li-Zhi 1
Alterations in regional homogeneity of resting:state brain activity in patients wi.. Yang, Haichen 1
Ritonavir-boosted indinavir but not lopinavir inhibits erythrocytic stage Plasmodi.. Qin, Li 1
A sensitive lateral flow biosensor for Escherichia coli O157:H7 detection based on.. Wu, Wei 1
Rosa26-targeted swine models for stable gene over-expression and Cre-mediated line.. Li, Xiaoping 1
Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivativ.. Liao, Sheng-Rong 1
Pd-Catalyzed One-Pot Synthesis of Polysubstituted Acrylamidines from Isocyanides, .. Yan, Xu 1
Eight new polyketide metabolites from the fungus Pestalotiopsis vaccinii endogenou.. Wang, Junfeng 1
Geochemical Explication of Sulfur Organics Characterized by Fourier Transform Ion .. Lu, Hong 1
Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associate.. Chen, Xin-Mei 1
Valproic Acid-Induced Hepatotoxicity in Alpers Syndrome Is Associated With Mitocho.. Li, Shengbiao 1
A Drosophila-centric view of protein tyrosine phosphatases Hatzihristidis, Teri 1
CRYOTHERAPY PROTOCOLS FOR METASTATIC BREAST CANCER AFTER FAILURE OF RADICAL SURGER.. Niu, L. 1
Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells Song, Yangyang 1
Evolution of Influenza A H7N9 Virus with an Emphasis on Gene Constellation Yang, Zifeng 1
Histone methyltransferase Dot1L plays a role in postembryonic development in Xenop.. Wen, Luan 1
Design, Synthesis and Antitubercular Evaluation of New 2-amino-5-(4-(benzyloxy)ben.. Lu, Xiaoyun 1
Differential expression analysis of Liprin-alpha 2 in hibernating bat (Rhinolophus.. Yuan, Lihong 1
New benzimidazole-2-urea derivates as tubulin inhibitors Wang, Wenna 1
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 an.. Tang, Jian-Jun ab 1
A convenient plasmid-based system containing three reporter genes for real-time an.. Feng, Liqiang 1
Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin.. Zhu, Yiguang 1
Activation of 5-HT2A/2C receptors reduces the excitability of cultured cortical ne.. Hu, Lingli 1
Largazole, an inhibitor of class I histone deacetylases, attenuates inflammatory c.. Zhou, Hongyan 1
Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based th.. Hu, Jiong 1
Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem c.. Wang, Jinyong 1
Functional Identification of Close Proximity Amino Acid Side Chains within the Tra.. Liang, Xin 1
Novel solvent-controlled chemoselective palladium/copper(II) halide catalyzed olig.. Cheng, Jin-Sheng 1
A specific drug targeting system based on polyhydroxyalkanoate granule binding pro.. Yao, Yong-Chao 1
Activation of 5-HT2A/C receptor reduces glycine receptor-mediated currents in cult.. Luo, Bin 1
Expression, Purification, Characterization and In Vitro Activity of Recombinant Mo.. Zhang, Zide 1
An integrated cell culture and quantitative polymerase chain reaction technique fo.. Li, Feng 1
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Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraft.. Ye, Wei 1
Geochemical Explication of Sulfur Organics Characterized by Fourier Transform Ion .. Lu, Hong 1
Pentafluorosulfanyl-Substituted Benzopyran Analogues As New Cyclooxygenase-2 Inhib.. Zhang, Yanmei 1
Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-.. Lu, Xiaoyun 1
DNA repair and replication links to pluripotency and differentiation capacity of p.. Liu, Kai 1
Selectively lighting up two-photon photodynamic activity in mitochondria with AIE-.. Liu, Jiangping 1
Enhanced cancer therapy by the marriage of metabolic alteration and mitochondrial-.. Liu, Jiangping 1
Regio and Enantioselective Organocatalytic Friedel-Crafts Alkylation of 4-Aminoind.. Xun, Wen 1
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian .. Wu, Han 1